產(chǎn)品編號(hào) | D58195 |
英文名稱(chēng) | BRD6989 |
中文名稱(chēng) | |
CAS | 642008-81-9 |
理論分子量 | 264.33 kDa |
檢測(cè)分子量 | |
保存條件 | Powder: -20℃ for 3 years | In solvent: -80℃ for 1 year |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
產(chǎn)品介紹 |
BRD6989 is an analog of the natural product cortistatin A (dCA). Which inhibits CDK8 and upregulates IL-10. BRD6989 inhibits the kinase activity of recombinant CDK8 or CDK19 complexes. BRD6989 selectively binds a complex of CDK8 with an IC50 of ~200 nM. |