| 產(chǎn)品編號(hào) | D62146 |
| 英文名稱 | GeA-69 |
| 中文名稱 | |
| CAS | 2143475-98-1 |
| 理論分子量 | 300.35 kDa |
| 檢測(cè)分子量 | |
| 保存條件 | 2-8℃ |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 |
GeA-69 is a selective, allosteric inhibitor of poly-adenosine-diphosphate-ribose polymerase 14 (PARP14) targeting macrodomain 2 (MD2), with a Kd value of 2.1 μM. GeA-69 involves in DNA damage repair mechanisms and prevents recruitment of PARP14 MD2 to sites of laser-induced DNA damage |
