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NAS6 Rabbit pAb (bs-19025R)  
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50ul/1180.00元
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200ul/2800.00元
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產品編號 bs-19025R
英文名稱 NAS6 Rabbit pAb
中文名稱 釀酒酵母NAS6蛋白抗體
別    名 Nas6p; PSD10_YEAST; YGR232W; G8564; ortholog of human oncoprotein gankyrin, which interacts with the Rb tumor suppressor and CDK4/6; Probable 26S proteasome regulatory subunit p28; Proteasome interacting protein involved in the assembly of the base subcomplex of the 19S proteasomal regulatory particle(RP); Proteasome non ATPase subunit 6.  
研究領域 微生物學  細菌及病毒  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Saccharomyces cerevisiae)
產品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 26 kDa
檢測分子量
細胞定位 細胞核 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from Saccharomyces cerevisiae NAS6: 41-140/228 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 NAS6 (p28) is a proteasome-interacting protein which acts as a chaperone to assemble the base sub-complex of the 19S RP which is involved in the ATP-dependent degradation of ubiquitinated proteins. NAS6 is composed of 226 amino acid residues with calculated molecular masses of 24.4kD.

Function:
Acts as a chaperone during the assembly of the 26S proteasome, specifically of the 19S regulatory complex (RC) and appears to have an overlapping role with RPN14.

Subunit:
Interacts with RPT3.

Subcellular Location:
Cytosol; Nucleus; Proteasome complex

Similarity:
Contains 6 ANK repeats.

Database links:

Entrez Gene: 853147 Saccharomyces cerevisiae

SwissProt: P50086 Saccharomyces cerevisiae



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