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Rabbit Anti-SECTM1  antibody (bs-10153R)
~~~促銷代碼KT202410~~~
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產(chǎn)品編號 bs-10153R
英文名稱 Rabbit Anti-SECTM1  antibody
中文名稱 分泌和跨膜蛋白1抗體
別    名 K12; K12 protein; Protein K-12; Protein K12; SCTM1_HUMAN; Secreted and transmembrane 1; Secreted and transmembrane protein 1; SECTM 1; SECTM1; Type 1a transmembrane protein.  
Specific References  (1)     |     bs-10153R has been referenced in 1 publications.
[IF=5.988] Wei Yu. et al. Identification and validation of key biomarkers for the early diagnosis of diabetic kidney disease.. FRONT PHARMACOL. 2022 Aug;13:931282-931282  IHC, WB ;  Mouse, Human.  
研究領(lǐng)域 腫瘤  細胞生物  免疫學  信號轉(zhuǎn)導  通道蛋白  腫瘤細胞生物標志物  細胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Rat (predicted: Human)
產(chǎn)品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 24kDa
細胞定位 細胞膜 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SECTM1: 42-150/248 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Detected at the highest levels in peripheral blood leukocytes and breast cancer cell lines. Found in leukocytes of the myeloid lineage, with the strongest expression observed in granulocytes and no detectable expression in lymphocytes. Expressed in thymic epithelial cells and fibroblasts.Belongs to the SECTM family.

Function:
May be involved in thymocyte signaling.

Subunit:
Interacts with CD7.

Subcellular Location:
Cell membrane. Secreted.

Tissue Specificity:
Detected at the highest levels in peripheral blood leukocytes and breast cancer cell lines. Found in leukocytes of the myeloid lineage, with the strongest expression observed in granulocytes and no detectable expression in lymphocytes. Expressed in thymic epithelial cells and fibroblasts.

DISEASE:
Detected at the highest levels in peripheral blood leukocytes and breast cancer cell lines. Found in leukocytes of the myeloid lineage, with the strongest expression observed in granulocytes and no detectable expression in lymphocytes. Expressed in thymic epithelial cells and fibroblasts.

Similarity:
Belongs to the SECTM family.

SWISS:
Q8WVN6

Gene ID:
6398

Database links:

Entrez Gene: 6398 Human

Omim: 602602 Human

SwissProt: Q8WVN6 Human

Unigene: 558009 Human



產(chǎn)品圖片
Tissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-SECTM1 Polyclonal Antibody, Unconjugated(bs-10153R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
Paraformaldehyde-fixed, paraffin embedded (rat live); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (SECTM1) Polyclonal Antibody, Unconjugated (bs-10153R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Paraformaldehyde-fixed, paraffin embedded (rat liver); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (SECTM1) Polyclonal Antibody, Unconjugated (bs-10153R ) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (pv-0023) instructionsand DAB staining.
Paraformaldehyde-fixed, paraffin embedded (rat liver); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (SECTM1) Polyclonal Antibody, Unconjugated (bs-10153R ) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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